

| Numéro de catalogue | HS845014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human TRIP11 Polyclonal Antibody (HS845014) is a rabbit polyclonal antibody detecting TRIP11 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human TRIP11 (Gln14-Tyr148). | ||||||||
| Cible | TRIP-11, CEV14, TR-interacting protein 11, Thyroid receptor-interacting protein 11, Golgi-associated microtubule-binding protein 210, Clonal evolution-related gene on chromosome 14 protein, Trip230, TRIP11, GMAP-210 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q15643 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Thyroid receptor-interacting protein 11 (TRIP11) is a ~227 kDa protein. Is a membrane tether required for vesicle tethering to Golgi. Has an essential role in the maintenance of Golgi structure and function. It is required for efficient anterograde and retrograde trafficking in the early secretory pathway, functioning at both the ER-to-Golgi intermediate compartment (ERGIC) and Golgi complex. Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB-modulated transcription. 1. Sato, K. et al. (2015) Molecular biology of the cell 26, 537-53. PMID: 25473115 2. Wehrle, A. et al. (2019) JCI insight 4. PMID: 30728324 3. Roboti, P. et al. (2015) Journal of cell science 128, 1595-606. PMID: 25717001 | ||||||||
| Note | For research use only. |
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