

| カタログ番号 | HS845014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human TRIP11 Polyclonal Antibody (HS845014) is a rabbit polyclonal antibody detecting TRIP11 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human TRIP11 (Gln14-Tyr148). | ||||||||
| ターゲット | TRIP-11, CEV14, TR-interacting protein 11, Thyroid receptor-interacting protein 11, Golgi-associated microtubule-binding protein 210, Clonal evolution-related gene on chromosome 14 protein, Trip230, TRIP11, GMAP-210 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q15643 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Thyroid receptor-interacting protein 11 (TRIP11) is a ~227 kDa protein. Is a membrane tether required for vesicle tethering to Golgi. Has an essential role in the maintenance of Golgi structure and function. It is required for efficient anterograde and retrograde trafficking in the early secretory pathway, functioning at both the ER-to-Golgi intermediate compartment (ERGIC) and Golgi complex. Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB-modulated transcription. 1. Sato, K. et al. (2015) Molecular biology of the cell 26, 537-53. PMID: 25473115 2. Wehrle, A. et al. (2019) JCI insight 4. PMID: 30728324 3. Roboti, P. et al. (2015) Journal of cell science 128, 1595-606. PMID: 25717001 | ||||||||
| 注意事項 | For research use only. |
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