

| Каталожный номер | HS845014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human TRIP11 Polyclonal Antibody (HS845014) is a rabbit polyclonal antibody detecting TRIP11 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human TRIP11 (Gln14-Tyr148). | ||||||||
| Цель | TRIP-11, CEV14, TR-interacting protein 11, Thyroid receptor-interacting protein 11, Golgi-associated microtubule-binding protein 210, Clonal evolution-related gene on chromosome 14 protein, Trip230, TRIP11, GMAP-210 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q15643 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Thyroid receptor-interacting protein 11 (TRIP11) is a ~227 kDa protein. Is a membrane tether required for vesicle tethering to Golgi. Has an essential role in the maintenance of Golgi structure and function. It is required for efficient anterograde and retrograde trafficking in the early secretory pathway, functioning at both the ER-to-Golgi intermediate compartment (ERGIC) and Golgi complex. Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB-modulated transcription. 1. Sato, K. et al. (2015) Molecular biology of the cell 26, 537-53. PMID: 25473115 2. Wehrle, A. et al. (2019) JCI insight 4. PMID: 30728324 3. Roboti, P. et al. (2015) Journal of cell science 128, 1595-606. PMID: 25717001 | ||||||||
| Примечание | For research use only. |
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