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Anti-Human TRPV6/ECaC2 Polyclonal Antibody (HP583014)

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Vista general
Número de catálogoHP583014
Descripción
Anti-Human TRPV6/ECaC2 Polyclonal Antibody (HP583014) is a rabbit polyclonal antibody detecting TRPV6/ECaC2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human TRPV6/ECaC2 (Ser87-Asp319).
Objetivo CaT1, Transient receptor potential cation channel subfamily V member 6, CaT-like, TrpV6, CaT-L, ECAC2, TRPV6, ECaC2, Epithelial calcium channel 2, Calcium transport protein 1
Purificación Purified by antigen affinity column.
Número de acceso Q9H1D0
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Transient receptor potential cation channel subfamily V member 6 (TRPV6/ECaC2) is a ~87 kDa protein. Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine. Important for normal Ca(2+) ion homeostasis in the body, including bone and skin. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner.

1. Peng, JB. et al. (2000) Biochemical and biophysical research communications 278, 326-32. PMID: 11097838
2. Niemeyer, BA. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 3600-5. PMID: 11248124
3. Wissenbach, U. et al. (2001) The Journal of biological chemistry 276, 19461-8. PMID: 11278579
4. Bödding, M. et al. (2004) The Journal of biological chemistry 279, 36546-52. PMID: 15184369
5. Fecher-Trost, C. et al. (2013) The Journal of biological chemistry 288, 16629-16644. PMID: 23612980
6. McGoldrick, LL. et al. (2018) Nature 553, 233-237. PMID: 29258289
Nota For research use only.
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Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human TRPV6/ECaC2 Polyclonal Antibody

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