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Anti-Human TRPV6/ECaC2 Polyclonal Antibody (HP583014)

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Aperçu
Numéro de catalogueHP583014
Description
Anti-Human TRPV6/ECaC2 Polyclonal Antibody (HP583014) is a rabbit polyclonal antibody detecting TRPV6/ECaC2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human TRPV6/ECaC2 (Ser87-Asp319).
Cible CaT1, Transient receptor potential cation channel subfamily V member 6, CaT-like, TrpV6, CaT-L, ECAC2, TRPV6, ECaC2, Epithelial calcium channel 2, Calcium transport protein 1
Purification Purified by antigen affinity column.
Numéro d'accès Q9H1D0
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Transient receptor potential cation channel subfamily V member 6 (TRPV6/ECaC2) is a ~87 kDa protein. Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine. Important for normal Ca(2+) ion homeostasis in the body, including bone and skin. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner.

1. Peng, JB. et al. (2000) Biochemical and biophysical research communications 278, 326-32. PMID: 11097838
2. Niemeyer, BA. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 3600-5. PMID: 11248124
3. Wissenbach, U. et al. (2001) The Journal of biological chemistry 276, 19461-8. PMID: 11278579
4. Bödding, M. et al. (2004) The Journal of biological chemistry 279, 36546-52. PMID: 15184369
5. Fecher-Trost, C. et al. (2013) The Journal of biological chemistry 288, 16629-16644. PMID: 23612980
6. McGoldrick, LL. et al. (2018) Nature 553, 233-237. PMID: 29258289
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human TRPV6/ECaC2 Polyclonal Antibody

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