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Anti-Human TSPAN14 Polyclonal Antibody (HD404014)

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Vista general
Número de catálogoHD404014
Descripción
Anti-Human TSPAN14 Polyclonal Antibody (HD404014) is a rabbit polyclonal antibody detecting TSPAN14. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human TSPAN14 (Leu114-Asn232).
Objetivo DC-TM4F2, TM4SF14, TSPAN14, Tetraspanin-14, Transmembrane 4 superfamily member 14, Tspan-14
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q8NG11
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Tetraspanin-14 (TSPAN14) is a ~30 kDa protein. Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Negatively regulates ADAM10-mediated cleavage of GP6. Promotes ADAM10-mediated cleavage of CDH5.

1. Haining, EJ. et al. (2012) The Journal of biological chemistry 287, 39753-65. PMID: 23035126
2. Noy, PJ. et al. (2016) The Journal of biological chemistry 291, 3145-57. PMID: 26668317
3. Jouannet, S. et al. (2016) Cellular and molecular life sciences : CMLS 73, 1895-915. PMID: 26686862
4. Lipper, CH. et al. (2023) Cell 186, 3632-3641.e10. PMID: 37516108
Nota For research use only
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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