Anti-Human TSPAN15 Polyclonal Antibody (HF620014)

Name: Anti-Human TSPAN15 Polyclonal Antibody
Brand: abinScience
SKU: HF620014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HF620014

Description

Anti-Human TSPAN15 Polyclonal Antibody (HF620014) is a rabbit polyclonal antibody detecting TSPAN15 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human TSPAN15 (Thr115-Ala235).

Cible

Tetraspanin-15, Tspan-15, Tetraspan NET-7, Transmembrane 4 superfamily member 15, TSPAN15, NET7, TM4SF15, UNQ677/PRO1311

Purification

Purified by antigen affinity column.

Numéro d'accès

O95858

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Tetraspanin-15 (TSPAN15) is a ~33 kDa protein. Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Promotes ADAM10-mediated cleavage of CDH2. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity.

1. Jouannet, S. et al. (2016) Cellular and molecular life sciences : CMLS 73, 1895-915. PMID: 26686862

2. Shah, J. et al. (2018) Cell reports 25, 2132-2147.e7. PMID: 30463011

3. Eschenbrenner, E. et al. (2020) Life science alliance 3. PMID: 31792032

4. Lipper, CH. et al. (2022) Structure (London, England : 1993) 30, 206-214.e4. PMID: 34739841

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human TSPAN15 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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