Anti-Human TSPAN8 Recombinant Antibody (SAA1592) (HB737013)

Name: Anti-Human TSPAN8 Recombinant Antibody (SAA1592)
Brand: abinScience
SKU: HB737013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HB737013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1592

Cible

TSPAN8, Tspan-8, Tumor-associated antigen CO-029, TM4SF3, Transmembrane 4 superfamily member 3, Tetraspanin-8

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P19075

RRID

Anti-Human TSPAN8 Antibody (SAA1592) (abinScience Cat# HB737013, RRID:AB_3727353)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Tetraspanin-8 (TSPAN8) is a ~26 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, migration and protein trafficking. Promotes ADAM17-mediated TNF processing through recruitment of ADAM17 to tetraspanin-enriched micro-domains (TEMs). Forms a complex with RICTOR and integrin alpha3/ITGA3 to mediate mTORC2 activation and AKT1 phosphorylation leading to cell migration. Reduces apoptosis and autophagy induced by high glucose levels through forming a complex with mTOR and RICTOR.

1. Schmidt, F. et al. (2016) Biological chemistry. PMID: 27180357

2. Müller, M. et al. (2022) Cells 11. PMID: 36078095

3. Pan, SJ. et al. (2015) International journal of molecular sciences 16, 5363-74. PMID: 25761241

4. Zhuang, L. et al. (2022) Cell biology international 46, 1693-1703. PMID: 35904232

5. Min, J. et al. (2023) Cellular and molecular life sciences : CMLS 80, 154. PMID: 37204469

6. Zhu, Y. et al. (2023) Cancers 15. PMID: 37835445

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human TSPAN8 Antibody (SAA1592)

Reférences

Fiche technique

Anti-Human TSPAN8 Recombinant Antibody (SAA1592).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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