Anti-Human TUFM Polyclonal Antibody (HW446014)

Name: Anti-Human TUFM Polyclonal Antibody
Brand: abinScience
SKU: HW446014
Price: 96 USD
Availability: InStock

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Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HW446014

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human TUFM (Asp67-Gly452).

Objetivo

P43, Elongation factor Tu, mitochondrial, TUFM, EF-Tu

Purificación

Purified by antigen affinity column.

Número de acceso

P49411

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Elongation factor Tu, mitochondrial (TUFM) is a ~49 kDa protein. GTP hydrolase that promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Participates in mitochondrial translation. Also plays a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIGI-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy.

1. Lei, Y. et al. (2012) Immunity 36, 933-46. PMID: 22749352

2. Ding, B. et al. (2017) Cell host & microbe 21, 538-547.e4. PMID: 28407488

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-TUFM polyclonal antibody at 1μg/ml on various samples.
Lane 1: HepG2 cell lysate
Lane 2: K562 cell lysate
Lane 3: Mouse brain lysate
Lane 4: Mouse kidney lysate
Lane 5: Mouse liver lysate
Lane 6: Rat brain lysate
Lane 7: Rat kidney lysate
Lane 8: Rat liver lysate