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Anti-Human TUT7 Polyclonal Antibody (HC200014)

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Vista general
Número de catálogoHC200014
Descripción
Anti-Human TUT7 Polyclonal Antibody (HC200014) is a rabbit polyclonal antibody detecting TUT7. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human TUT7 (Lys996-Arg1379).
Objetivo EC:2.7.7.52, HS2, KIAA1711, TUT7, TUTase 7, Terminal uridylyltransferase 7, ZCCHC6, Zinc finger CCHC domain-containing protein 6
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q5VYS8
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Terminal uridylyltransferase 7 (TUT7) is a ~171 kDa protein. Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay. Essential for both oocyte maturation and fertility. Through 3' terminal uridylation of mRNA, sculpts, with TUT7, the maternal transcriptome by eliminating transcripts during oocyte growth. Involved in microRNA (miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets. Also functions as an integral regulator of microRNA biogenesiS using 3 different uridylation mechanisms.

1. Heo, I. et al. (2009) Cell 138, 696-708. PMID: 19703396
2. Lim, J. et al. (2014) Cell 159, 1365-76. PMID: 25480299
3. Kim, B. et al. (2015) The EMBO journal 34, 1801-15. PMID: 25979828
4. Thornton, JE. et al. (2012) RNA (New York, N.Y.) 18, 1875-85. PMID: 22898984
5. Faehnle, CR. et al. (2017) Nature structural & molecular biology 24, 658-665. PMID: 28671666
6. Mullen, TE. et al. (2008) Genes & development 22, 50-65. PMID: 18172165
Nota For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human TUT7 Polyclonal Antibody

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