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| カタログ番号 | HB884013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human, Mouse, Rat | ||||
| アプリケーション | IF, WB | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | TA99 | ||||
| ターゲット | 5, 6-dihydroxyindole-2-carboxylic acid oxidase, Glycoprotein 75, CAS2, TYRP1, TRP-1, TYRRP, TRP1, Catalase B, TYRP, Melanoma antigen gp75, TRP, DHICA oxidase, Tyrosinase-related protein 1 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P17643 | ||||
| RRID | Anti-Human TYRP1 Antibody (TA99) (abinScience Cat# HB884013, RRID:AB_3725672) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | 5,6-dihydroxyindole-2-carboxylic acid oxidase (TYRP1) is a ~60 kDa protein. Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions, but not in the presence of Zn(2+). May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin. 1. Rooryck, C. et al. (2006) Pigment cell research 19, 239-42. PMID: 16704458 2. Kenny, EE. et al. (2012) Science (New York, N.Y.) 336, 554. PMID: 22556244 3. Simeonov, DR. et al. (2013) Human mutation 34, 827-35. PMID: 23504663 4. Lai, X. et al. (2017) Angewandte Chemie (International ed. in English) 56, 9812-9815. PMID: 28661582 | ||||
| 注意事項 | For research use only. | ||||
| Isotype Control | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507) Mouse IgG2a Recombinant Isotype Control Antibody (S43.10) (MF533307) |
SDS-PAGE for Anti-Human TYRP1 Antibody (TA99).
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