

| Numéro de catalogue | HA110014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human UBASH3B Polyclonal Antibody (HA110014) is a rabbit polyclonal antibody detecting UBASH3B in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human UBASH3B (Gln382-Asp626). | ||||||||
| Cible | Tyrosine-protein phosphatase STS1/TULA2, TULA-2, STS1, Suppressor of T-cell receptor signaling 1, Ubiquitin-associated and SH3 domain-containing protein B, Cbl-interacting protein p70, STS-1, T-cell ubiquitin ligand 2, KIAA1959, UBASH3B | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q8TF42 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Ubiquitin-associated and SH3 domain-containing protein B (UBASH3B) is a ~72 kDa protein. Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination. | ||||||||
| Note | For research use only. |
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