

| Número de catálogo | HX857014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human UBE2K (Met1-Asn200). | ||||||||
| Objetivo | Ubiquitin-conjugating enzyme E2(25K), Ubiquitin-protein ligase, UBE2K, HIP-2, E2 ubiquitin-conjugating enzyme K, Huntingtin-interacting protein 2, Ubiquitin-conjugating enzyme E2-25K, Ubiquitin-conjugating enzyme E2 K, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2-25 kDa, HIP2, LIG | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P61086 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Ubiquitin-conjugating enzyme E2 K (UBE2K) is a ~22 kDa protein. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. | ||||||||
| Nota | For research use only. |
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