Anti-Human UBE2T Polyclonal Antibody (HP958014)

Name: Anti-Human UBE2T Polyclonal Antibody
Brand: abinScience
SKU: HP958014
Price: 168 USD
Availability: InStock

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100ug

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Fiche technique
SDS

Aperçu

Numéro de catalogue

HP958014

Description

Anti-Human UBE2T Polyclonal Antibody (HP958014) is a rabbit polyclonal antibody detecting UBE2T in ELISA, IHC, WB. Suitable for Bovine, Human, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human UBE2T (Met1-Arg152).

Cible

Ubiquitin-protein ligase T, Ubiquitin carrier protein T, UBE2T, Cell proliferation-inducing gene 50 protein, Ubiquitin-conjugating enzyme E2 T, E2 ubiquitin-conjugating enzyme T

Purification

Purified by antigen affinity column.

Numéro d'accès

Q9NPD8

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Ubiquitin-conjugating enzyme E2 T (UBE2T) is a ~22 kDa protein. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair. Acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI.

1. Machida, YJ. et al. (2006) Molecular cell 23, 589-96. PMID: 16916645

2. Alpi, A. et al. (2007) Molecular and cellular biology 27, 8421-30. PMID: 17938197

3. Alpi, AF. et al. (2008) Molecular cell 32, 767-77. PMID: 19111657

4. Longerich, S. et al. (2009) The Journal of biological chemistry 284, 23182-6. PMID: 19589784

5. Morreale, FE. et al. (2017) Journal of medicinal chemistry 60, 4093-4098. PMID: 28437106

6. Ueki, T. et al. (2009) Cancer research 69, 8752-60. PMID: 19887602

7. David, Y. et al. (2010) The Journal of biological chemistry 285, 8595-604. PMID: 20061386

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human UBE2T Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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