Anti-Human UBE2T Polyclonal Antibody (HP958014)

Name: Anti-Human UBE2T Polyclonal Antibody
Brand: abinScience
SKU: HP958014
Price: 168 USD
Availability: InStock

データシート製品共有情報コピー

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100ug

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HP958014

説明

Anti-Human UBE2T Polyclonal Antibody (HP958014) is a rabbit polyclonal antibody detecting UBE2T in ELISA, IHC, WB. Suitable for Bovine, Human, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human UBE2T (Met1-Arg152).

ターゲット

Ubiquitin-protein ligase T, Ubiquitin carrier protein T, UBE2T, Cell proliferation-inducing gene 50 protein, Ubiquitin-conjugating enzyme E2 T, E2 ubiquitin-conjugating enzyme T

精製

Purified by antigen affinity column.

アクセッション番号

Q9NPD8

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Ubiquitin-conjugating enzyme E2 T (UBE2T) is a ~22 kDa protein. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair. Acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI.

1. Machida, YJ. et al. (2006) Molecular cell 23, 589-96. PMID: 16916645

2. Alpi, A. et al. (2007) Molecular and cellular biology 27, 8421-30. PMID: 17938197

3. Alpi, AF. et al. (2008) Molecular cell 32, 767-77. PMID: 19111657

4. Longerich, S. et al. (2009) The Journal of biological chemistry 284, 23182-6. PMID: 19589784

5. Morreale, FE. et al. (2017) Journal of medicinal chemistry 60, 4093-4098. PMID: 28437106

6. Ueki, T. et al. (2009) Cancer research 69, 8752-60. PMID: 19887602

7. David, Y. et al. (2010) The Journal of biological chemistry 285, 8595-604. PMID: 20061386

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-Human UBE2T Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human UBE2T Polyclonal Antibody (HP958014)

概要

イメージ

参考文献

データシート

SDS

クイックアクセス

お問い合わせ