

| Numéro de catalogue | HD151014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human UBE4B Polyclonal Antibody (HD151014) is a rabbit polyclonal antibody detecting UBE4B. Suitable for Human and Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human UBE4B (Leu961-His1302). | ||||||||
| Cible | EC:2.3.2.27, HDNB1, Homozygously deleted in neuroblastoma 1, KIAA0684, RING-type E3 ubiquitin transferase E4 B, UBE4B, UFD2, Ubiquitin conjugation factor E4 B, Ubiquitin fusion degradation protein 2 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O95155 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Ubiquitin conjugation factor E4 B (UBE4B) is a ~146 kDa protein. Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. May regulate myosin assembly in striated muscles together with STUB1 and VCP/p97 by targeting myosin chaperone UNC45B for proteasomal degradation. 1. Janiesch, PC. et al. (2007) Nature cell biology 9, 379-90. PMID: 17369820 | ||||||||
| Note | For research use only |

Western blot analysis was performed using anti-UBE4B polyclonal antibody at 1ug/mL on various samples.
Lane 1: RAW264.7 cell lysate
Lane 2: C2C12 cell lysate
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