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| カタログ番号 | HD151014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human UBE4B Polyclonal Antibody (HD151014) is a rabbit polyclonal antibody detecting UBE4B. Suitable for Human and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human UBE4B (Leu961-His1302). | ||||||||
| ターゲット | EC:2.3.2.27, HDNB1, Homozygously deleted in neuroblastoma 1, KIAA0684, RING-type E3 ubiquitin transferase E4 B, UBE4B, UFD2, Ubiquitin conjugation factor E4 B, Ubiquitin fusion degradation protein 2 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O95155 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Ubiquitin conjugation factor E4 B (UBE4B) is a ~146 kDa protein. Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. May regulate myosin assembly in striated muscles together with STUB1 and VCP/p97 by targeting myosin chaperone UNC45B for proteasomal degradation. 1. Janiesch, PC. et al. (2007) Nature cell biology 9, 379-90. PMID: 17369820 | ||||||||
| 注意事項 | For research use only |
Western blot analysis was performed using anti-UBE4B polyclonal antibody at 1ug/mL on various samples.
Lane 1: RAW264.7 cell lysate
Lane 2: C2C12 cell lysate
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