

| Número de catálogo | HA400014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human UGDH Polyclonal Antibody (HA400014) is a rabbit polyclonal antibody detecting UGDH. Suitable for Human, Rat, and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human UGDH (Met1-Val494). | ||||||||
| Objetivo | EC:1.1.1.22, UDP-Glc dehydrogenase, UDP-GlcDH, UDP-glucose 6-dehydrogenase, UDPGDH, UGDH | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O60701 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | UDP-glucose 6-dehydrogenase (UGDH) is a ~55 kDa protein. Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans. Required for proper brain and neuronal development. 1. Egger, S. et al. (2011) The Journal of biological chemistry 286, 23877-87. PMID: 21502315 2. Sennett, NC. et al. (2011) Biochemistry 50, 9651-63. PMID: 21961565 3. Egger, S. et al. (2012) The Journal of biological chemistry 287, 2119-29. PMID: 22123821 4. Sennett, NC. et al. (2012) Biochemistry 51, 9364-74. PMID: 23106432 5. Kadirvelraj, R. et al. (2014) Biochemistry 53, 8043-51. PMID: 25478983 6. Beattie, NR. et al. (2017) Biochemistry 56, 202-211. PMID: 27966912 7. Keul, ND. et al. (2018) Nature 563, 584-588. PMID: 30420606 8. Beattie, NR. et al. (2018) Biochemistry 57, 6848-6859. PMID: 30457329 9. Hengel, H. et al. (2020) Nature communications 11, 595. PMID: 32001716 | ||||||||
| Nota | For research use only |
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