

| Número de catálogo | HY326014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human UROD Polyclonal Antibody (HY326014) is a rabbit polyclonal antibody detecting UROD in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human UROD (Met1-Asn367). | ||||||||
| Objetivo | Uroporphyrinogen decarboxylase, UPD, URO-D, 4.1.1.37, UROD | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P06132 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Uroporphyrinogen decarboxylase (UROD) is a ~40 kDa protein. Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway. Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme. In vitro also decarboxylates pentacarboxylate porphyrinogen I. 1. Brady, JJ. et al. (2000) The Journal of investigative dermatology 115, 868-74. PMID: 11069625 2. Phillips, JD. et al. (2001) Blood 98, 3179-85. PMID: 11719352 3. Phillips, JD. et al. (2003) The EMBO journal 22, 6225-33. PMID: 14633982 4. Cunha, L. et al. (2008) Proteins 71, 855-73. PMID: 18004775 5. To-Figueras, J. et al. (2011) The British journal of dermatology 165, 499-505. PMID: 21668429 6. Ged, C. et al. (2002) Archives of dermatology 138, 957-60. PMID: 12071824 | ||||||||
| Nota | For research use only. |
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