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Anti-Human UROD Polyclonal Antibody (HY326014)

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概要
カタログ番号HY326014
説明
Anti-Human UROD Polyclonal Antibody (HY326014) is a rabbit polyclonal antibody detecting UROD in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
種反応性Human, Mouse
アプリケーションELISA, IHC, WB
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 E. coli - derived recombinant Human UROD (Met1-Asn367).
ターゲット Uroporphyrinogen decarboxylase, UPD, URO-D, 4.1.1.37, UROD
精製 Purified by antigen affinity column.
アクセッション番号 P06132
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Uroporphyrinogen decarboxylase (UROD) is a ~40 kDa protein. Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway. Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme. In vitro also decarboxylates pentacarboxylate porphyrinogen I.

1. Brady, JJ. et al. (2000) The Journal of investigative dermatology 115, 868-74. PMID: 11069625
2. Phillips, JD. et al. (2001) Blood 98, 3179-85. PMID: 11719352
3. Phillips, JD. et al. (2003) The EMBO journal 22, 6225-33. PMID: 14633982
4. Cunha, L. et al. (2008) Proteins 71, 855-73. PMID: 18004775
5. To-Figueras, J. et al. (2011) The British journal of dermatology 165, 499-505. PMID: 21668429
6. Ged, C. et al. (2002) Archives of dermatology 138, 957-60. PMID: 12071824
注意事項 For research use only.
イメージ
参考文献
Formula
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