

| カタログ番号 | HY326014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human UROD Polyclonal Antibody (HY326014) is a rabbit polyclonal antibody detecting UROD in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human UROD (Met1-Asn367). | ||||||||
| ターゲット | Uroporphyrinogen decarboxylase, UPD, URO-D, 4.1.1.37, UROD | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P06132 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Uroporphyrinogen decarboxylase (UROD) is a ~40 kDa protein. Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway. Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme. In vitro also decarboxylates pentacarboxylate porphyrinogen I. 1. Brady, JJ. et al. (2000) The Journal of investigative dermatology 115, 868-74. PMID: 11069625 2. Phillips, JD. et al. (2001) Blood 98, 3179-85. PMID: 11719352 3. Phillips, JD. et al. (2003) The EMBO journal 22, 6225-33. PMID: 14633982 4. Cunha, L. et al. (2008) Proteins 71, 855-73. PMID: 18004775 5. To-Figueras, J. et al. (2011) The British journal of dermatology 165, 499-505. PMID: 21668429 6. Ged, C. et al. (2002) Archives of dermatology 138, 957-60. PMID: 12071824 | ||||||||
| 注意事項 | For research use only. |
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