

| Numéro de catalogue | HY300014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human UROS Polyclonal Antibody (HY300014) is a rabbit polyclonal antibody detecting UROS in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human UROS (Met1-Cys265). | ||||||||
| Cible | Uroporphyrinogen-III synthase, UROIIIS, UROS, 4.2.1.75, Hydroxymethylbilane hydrolyase [cyclizing], Uroporphyrinogen-III cosynthase, UROS | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P10746 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Uroporphyrinogen-III synthase (UROS) is a ~28 kDa protein. Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme). 1. Mathews, MA. et al. (2001) The EMBO journal 20, 5832-9. PMID: 11689424 2. Cunha, L. et al. (2008) Proteins 71, 855-73. PMID: 18004775 | ||||||||
| Note | For research use only. |
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