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| カタログ番号 | HY300014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human UROS Polyclonal Antibody (HY300014) is a rabbit polyclonal antibody detecting UROS in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human UROS (Met1-Cys265). | ||||||||
| ターゲット | Uroporphyrinogen-III synthase, UROIIIS, UROS, 4.2.1.75, Hydroxymethylbilane hydrolyase [cyclizing], Uroporphyrinogen-III cosynthase, UROS | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P10746 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Uroporphyrinogen-III synthase (UROS) is a ~28 kDa protein. Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme). 1. Mathews, MA. et al. (2001) The EMBO journal 20, 5832-9. PMID: 11689424 2. Cunha, L. et al. (2008) Proteins 71, 855-73. PMID: 18004775 | ||||||||
| 注意事項 | For research use only. |
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