Anti-Human USP1 Polyclonal Antibody (HF660014)

Name: Anti-Human USP1 Polyclonal Antibody
Brand: abinScience
SKU: HF660014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HF660014

Description

Anti-Human USP1 Polyclonal Antibody (HF660014) is a rabbit polyclonal antibody detecting USP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human USP1 (Arg486-Lys599).

Cible

Ubiquitin thioesterase 1, Ubiquitin carboxyl-terminal hydrolase 1, Deubiquitinating enzyme 1, Ubiquitin-specific-processing protease 1, USP1, hUBP

Purification

Purified by antigen affinity column.

Numéro d'accès

O94782

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Ubiquitin carboxyl-terminal hydrolase 1 (USP1) is a ~88 kDa protein. Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2. Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity.

1. Nijman, SM. et al. (2005) Molecular cell 17, 331-9. PMID: 15694335

2. Huang, TT. et al. (2006) Nature cell biology 8, 339-47. PMID: 16531995

3. Lee, KY. et al. (2010) The Journal of biological chemistry 285, 10362-9. PMID: 20147293

4. Cohn, MA. et al. (2007) Molecular cell 28, 786-97. PMID: 18082604

5. Yin, J. et al. (2015) Structure (London, England : 1993) 23, 2043-54. PMID: 26388029

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human USP1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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