Anti-Human USP11 Polyclonal Antibody (HW368014)

Name: Anti-Human USP11 Polyclonal Antibody
Brand: abinScience
SKU: HW368014
Price: 96 USD
Availability: InStock

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Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HW368014

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human USP11 (Gly77-Asn292).

Objetivo

Ubiquitin-specific-processing protease 11, Deubiquitinating enzyme 11, UHX1, USP11, Ubiquitin carboxyl-terminal hydrolase 11, Ubiquitin thioesterase 11

Purificación

Purified by antigen affinity column.

Número de acceso

P51784

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Ubiquitin carboxyl-terminal hydrolase 11 (USP11) is a ~109 kDa protein. Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro). Plays a role in the regulation of pathways leading to NF-kappa-B activation.

1. Ideguchi, H. et al. (2002) The Biochemical journal 367, 87-95. PMID: 12084015

2. Schoenfeld, AR. et al. (2004) Molecular and cellular biology 24, 7444-55. PMID: 15314155

3. Yamaguchi, T. et al. (2007) The Journal of biological chemistry 282, 33943-8. PMID: 17897950

4. Sun, W. et al. (2010) Cellular signalling 22, 386-94. PMID: 19874889

5. Wiltshire, TD. et al. (2010) The Journal of biological chemistry 285, 14565-71. PMID: 20233726

6. Harper, S. et al. (2014) Biochemistry 53, 2966-78. PMID: 24724799

7. Wang, D. et al. (2018) Journal of molecular cell biology 10, 60-73. PMID: 28992046

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human USP11 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo