Anti-Human USP19 Polyclonal Antibody (HF923014)

Name: Anti-Human USP19 Polyclonal Antibody
Brand: abinScience
SKU: HF923014
Price: 168 USD
Availability: InStock

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Каталожный номер

HF923014

Описание

Anti-Human USP19 Polyclonal Antibody (HF923014) is a rabbit polyclonal antibody detecting USP19 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human USP19 (Lys286-Gln376).

Цель

Deubiquitinating enzyme 19, Ubiquitin thioesterase 19, KIAA0891, ZMYND9, Ubiquitin carboxyl-terminal hydrolase 19, Ubiquitin-specific-processing protease 19, Zinc finger MYND domain-containing protein 9, USP19

Очистка

Purified by antigen affinity column.

Номер доступа

O94966

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Ubiquitin carboxyl-terminal hydrolase 19 (USP19) is a ~145 kDa protein. Deubiquitinating enzyme that regulates the degradation of various proteins by removing ubiquitin moieties, thereby preventing their proteasomal degradation. Stabilizes RNF123, which promotes CDKN1B degradation and contributes to cell proliferation. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates.

1. Hassink, GC. et al. (2009) EMBO reports 10, 755-61. PMID: 19465887

2. Lee, JG. et al. (2014) The Journal of biological chemistry 289, 3510-7. PMID: 24356957

3. Mei, Y. et al. (2011) The Journal of biological chemistry 286, 35380-35387. PMID: 21849505

4. Altun, M. et al. (2012) The Journal of biological chemistry 287, 1962-9. PMID: 22128162

5. Chai, P. et al. (2021) The Journal of cell biology 220. PMID: 33978709

6. Yu, W. et al. (2024) Journal of Alzheimer's disease : JAD 100, 799-808. PMID: 38943386

7. Lei, CQ. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 259-268. PMID: 31127032

8. Xue, W. et al. (2020) The Biochemical journal 477, 4295-4312. PMID: 33094816

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human USP19 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

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Anti-Human USP19 Polyclonal Antibody (HF923014)

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