

| Número de catálogo | HD622014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human USP34 Polyclonal Antibody (HD622014) is a rabbit polyclonal antibody detecting USP34. Suitable for Human and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human USP34 (Val1894-Met2239). | ||||||||
| Objetivo | Deubiquitinating enzyme 34, EC:3.4.19.12, KIAA0570, KIAA0729, USP34, Ubiquitin carboxyl-terminal hydrolase 34, Ubiquitin thioesterase 34, Ubiquitin-specific-processing protease 34 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q70CQ2 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Ubiquitin carboxyl-terminal hydrolase 34 (USP34) is a ~404 kDa protein. Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. | ||||||||
| Nota | For research use only |
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