Anti-Human USP4 Polyclonal Antibody (HC280014)

Name: Anti-Human USP4 Polyclonal Antibody
Brand: abinScience
SKU: HC280014
Price: 96 USD
Availability: InStock

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Número de catálogo

HC280014

Descripción

Anti-Human USP4 Polyclonal Antibody (HC280014) is a rabbit polyclonal antibody detecting USP4 in ELISA, IHC, WB. Suitable for Human, Bovine, Rat, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human USP4 (Asp12-Glu220).

Objetivo

Ubiquitin carboxyl-terminal hydrolase 4, 3.4.19.12, Deubiquitinating enzyme 4, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4, Ubiquitous nuclear protein homolog, USP4, UNP, UNPH

Nivel de endotoxinas

Please contact with the lab for this information.

Peso molecular observado

~110 kDa

Purificación

Purified by antigen affinity column.

Número de acceso

Q13107, A6QR55, B2GUZ1, P35123

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Ubiquitin carboxyl-terminal hydrolase 4 (USP4) is a ~108 kDa protein. Deubiquitinating enzyme that removes conjugated ubiquitin from target proteins. Deubiquitinates PDPK1. Deubiquitinates TRIM21. Deubiquitinates receptor ADORA2A which increases the amount of functional receptor at the cell surface. Deubiquitinates HAS2.

1. Wada, K. et al. (2006) Biochemical and biophysical research communications 339, 731-6. PMID: 16316627

2. Milojevic, T. et al. (2006) Molecular pharmacology 69, 1083-94. PMID: 16339847

3. Wada, K. et al. (2006) Biochemical and biophysical research communications 342, 253-8. PMID: 16472766

4. Song, EJ. et al. (2010) Genes & development 24, 1434-47. PMID: 20595234

5. Uras, IZ. et al. (2012) PloS one 7, e31003. PMID: 22347420

6. Clerici, M. et al. (2014) Nature communications 5, 5399. PMID: 25404403

7. Mehić, M. et al. (2017) Oncogenesis 6, e348. PMID: 28604766

8. Deng, L. et al. (2019) Cell research 29, 136-150. PMID: 30514904

9. Chu, F. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2401174121. PMID: 39589880

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-USP4 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: Jurkat cell lysate

Referencias

Datasheet

Anti-Human USP4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human USP4 Polyclonal Antibody (HC280014)

Vista general

Imágenes

Referencias

Datasheet

SDS