

| Número de catálogo | HP405014 | ||||||||
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| Descripción |
Anti-Human VANGL2 Polyclonal Antibody (HP405014) is a rabbit polyclonal antibody detecting VANGL2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human VANGL2 (Gln241-Lys493). | ||||||||
| Objetivo | STB1, VANGL2, Van Gogh-like protein 2, Loop-tail protein 1 homolog, KIAA1215, Vang-like protein 2, Strabismus 1 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9ULK5 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Vang-like protein 2 (VANGL2) is a ~59 kDa protein. Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear. | ||||||||
| Nota | For research use only. |
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