

| Número de catálogo | HP280013 | ||||
|---|---|---|---|---|---|
| Reactividad de especies | Human | ||||
| Aplicaciones | ELISA | ||||
| Especie huésped | Mouse | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG2a, kappa | ||||
| ID de clon | SAA1602 | ||||
| Objetivo | VASHL, Vasohibin-2, VASH2, Vasohibin-like protein, Tubulinyl-Tyr carboxypeptidase 2 | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | Q86V25 | ||||
| RRID | Anti-Human VASH2/Vasohibin-2 Antibody (SAA1602) (abinScience Cat# HP280013, RRID:AB_3727363) |
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| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Fondo | Tubulinyl-Tyr carboxypeptidase 2 (VASH2/Vasohibin-2) is a ~40 kDa protein. Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mitosis since microtubule detyronisation regulates mitotic spindle length and postioning. Acts as an activator of angiogenesis: expressed in infiltrating mononuclear cells in the sprouting front to promote angiogenesis. Plays a role in axon formation. 1. Nieuwenhuis, J. et al. (2017) Science (New York, N.Y.) 358, 1453-1456. PMID: 29146869 2. Liao, S. et al. (2019) Cell research 29, 533-547. PMID: 31171830 3. Kimura, H. et al. (2009) Blood 113, 4810-8. PMID: 19204325 4. Wang, N. et al. (2019) Nature structural & molecular biology 26, 571-582. PMID: 31235911 | ||||
| Nota | For research use only. |

SDS-PAGE for Anti-Human VASH2/Vasohibin-2 Antibody (SAA1602)
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