

| Numéro de catalogue | HP280013 | ||||
|---|---|---|---|---|---|
| Reactivité des espèces | Human | ||||
| Applications | ELISA | ||||
| Espèce hôte | Mouse | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG2a, kappa | ||||
| ID de clone | SAA1602 | ||||
| Cible | VASHL, Vasohibin-2, VASH2, Vasohibin-like protein, Tubulinyl-Tyr carboxypeptidase 2 | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | Q86V25 | ||||
| RRID | Anti-Human VASH2/Vasohibin-2 Antibody (SAA1602) (abinScience Cat# HP280013, RRID:AB_3727363) |
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| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Contexte | Tubulinyl-Tyr carboxypeptidase 2 (VASH2/Vasohibin-2) is a ~40 kDa protein. Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mitosis since microtubule detyronisation regulates mitotic spindle length and postioning. Acts as an activator of angiogenesis: expressed in infiltrating mononuclear cells in the sprouting front to promote angiogenesis. Plays a role in axon formation. 1. Nieuwenhuis, J. et al. (2017) Science (New York, N.Y.) 358, 1453-1456. PMID: 29146869 2. Liao, S. et al. (2019) Cell research 29, 533-547. PMID: 31171830 3. Kimura, H. et al. (2009) Blood 113, 4810-8. PMID: 19204325 4. Wang, N. et al. (2019) Nature structural & molecular biology 26, 571-582. PMID: 31235911 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human VASH2/Vasohibin-2 Antibody (SAA1602)
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