

| Numéro de catalogue | HD137014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human WAPL Polyclonal Antibody (HD137014) is a rabbit polyclonal antibody detecting WAPL. Suitable for Human and Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human WAPL (His641-Asp838). | ||||||||
| Cible | FOE, Friend of EBNA2 protein, KIAA0261, WAPAL, WAPL, WAPL cohesin release factor, Wings apart-like protein homolog | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q7Z5K2 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Wings apart-like protein homolog (WAPL) is a ~132 kDa protein. Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. 1. Yeh, C. et al. (2015) Current biology : CB 25, 2290-9. PMID: 26299517 | ||||||||
| Note | For research use only |
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