

| Numéro de catalogue | HP505014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human WBP2 Polyclonal Antibody (HP505014) is a rabbit polyclonal antibody detecting WBP2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human WBP2 (Met1-Gly136). | ||||||||
| Cible | WBP-2, WW domain-binding protein 2, WBP2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q969T9 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | WW domain-binding protein 2 (WBP2) is a ~28 kDa protein. Acts as a transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation. In presence of estrogen, binds to ESR1-responsive promoters. Synergizes with YAP1 to enhance PGR activity. Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR. 1. Dhananjayan, SC. et al. (2006) Molecular endocrinology (Baltimore, Md.) 20, 2343-54. PMID: 16772533 | ||||||||
| Note | For research use only. |
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