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Anti-Human WDR1 Polyclonal Antibody (HF897024)

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Vista general
Número de catálogoHF897024
Descripción
Anti-Human WDR1 Polyclonal Antibody (HF897024) is a rabbit polyclonal antibody detecting WDR1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Chicken.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human WDR1 (Met1-Lys317).
Objetivo WD repeat-containing protein 1, Actin-interacting protein 1, WDR1, AIP1, NORI-1
Purificación Purified by antigen affinity column.
Número de acceso O75083
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

WD repeat-containing protein 1 (WDR1) is a ~66 kDa protein. Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Enhances cofilin-mediated actin severing. Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions. Involved in myocardium sarcomere organization.

1. Fujibuchi, T. et al. (2005) Biochemical and biophysical research communications 327, 268-75. PMID: 15629458
2. Kuhns, DB. et al. (2016) Blood 128, 2135-2143. PMID: 27557945
3. Pfajfer, L. et al. (2018) The Journal of allergy and clinical immunology 142, 1589-1604.e11. PMID: 29751004
4. Kato, A. et al. (2008) The Biochemical journal 414, 261-70. PMID: 18494608
5. Lechuga, S. et al. (2015) American journal of physiology. Gastrointestinal and liver physiology 308, G745-56. PMID: 25792565
Nota For research use only.
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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