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Anti-Human WDR1 Polyclonal Antibody (HF897024)

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Aperçu
Numéro de catalogueHF897024
Description
Anti-Human WDR1 Polyclonal Antibody (HF897024) is a rabbit polyclonal antibody detecting WDR1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Chicken.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human WDR1 (Met1-Lys317).
Cible WD repeat-containing protein 1, Actin-interacting protein 1, WDR1, AIP1, NORI-1
Purification Purified by antigen affinity column.
Numéro d'accès O75083
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

WD repeat-containing protein 1 (WDR1) is a ~66 kDa protein. Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Enhances cofilin-mediated actin severing. Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions. Involved in myocardium sarcomere organization.

1. Fujibuchi, T. et al. (2005) Biochemical and biophysical research communications 327, 268-75. PMID: 15629458
2. Kuhns, DB. et al. (2016) Blood 128, 2135-2143. PMID: 27557945
3. Pfajfer, L. et al. (2018) The Journal of allergy and clinical immunology 142, 1589-1604.e11. PMID: 29751004
4. Kato, A. et al. (2008) The Biochemical journal 414, 261-70. PMID: 18494608
5. Lechuga, S. et al. (2015) American journal of physiology. Gastrointestinal and liver physiology 308, G745-56. PMID: 25792565
Note For research use only.
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Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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