

| Numéro de catalogue | HF897024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human WDR1 Polyclonal Antibody (HF897024) is a rabbit polyclonal antibody detecting WDR1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Chicken.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human WDR1 (Met1-Lys317). | ||||||||
| Cible | WD repeat-containing protein 1, Actin-interacting protein 1, WDR1, AIP1, NORI-1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O75083 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | WD repeat-containing protein 1 (WDR1) is a ~66 kDa protein. Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Enhances cofilin-mediated actin severing. Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions. Involved in myocardium sarcomere organization. 1. Fujibuchi, T. et al. (2005) Biochemical and biophysical research communications 327, 268-75. PMID: 15629458 2. Kuhns, DB. et al. (2016) Blood 128, 2135-2143. PMID: 27557945 3. Pfajfer, L. et al. (2018) The Journal of allergy and clinical immunology 142, 1589-1604.e11. PMID: 29751004 4. Kato, A. et al. (2008) The Biochemical journal 414, 261-70. PMID: 18494608 5. Lechuga, S. et al. (2015) American journal of physiology. Gastrointestinal and liver physiology 308, G745-56. PMID: 25792565 | ||||||||
| Note | For research use only. |



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