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Anti-Human WDR46 Polyclonal Antibody (HT164014)

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Anti-Human WDR46 Polyclonal Antibody
Anti-Human WDR46 Polyclonal Antibody
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Vista general
Número de catálogoHT164014
Descripción
Anti-Human WDR46 Polyclonal Antibody (HT164014) is a rabbit polyclonal antibody detecting WDR46 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human WDR46 (Lys187-Glu523).
Objetivo WDR46, C6orf11, BING4, WD repeat-containing protein BING4, WD repeat-containing protein 46
Purificación Purified by antigen affinity column.
Número de acceso O15213
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

WD repeat-containing protein 46 (WDR46) is a ~68 kDa protein. Scaffold component of the nucleolar structure. Required for localization of DDX21 and NCL to the granular compartment of the nucleolus. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.

1. Hirai, Y. et al. (2013) Genes to cells : devoted to molecular & cellular mechanisms 18, 780-97. PMID: 23848194
2. Singh, S. et al. (2021) Science (New York, N.Y.) 373, eabj5338. PMID: 34516797
Nota For research use only.
Imágenes
  • Anti-Human WDR46 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-WDR46 polyclonal antibody at 1μg/ml on various samples.
    Lane 1: Hela cell lysate

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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