Anti-Human WDR46 Polyclonal Antibody (HT164014)

Name: Anti-Human WDR46 Polyclonal Antibody
Brand: abinScience
SKU: HT164014
Price: 96 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HT164014

Description

Anti-Human WDR46 Polyclonal Antibody (HT164014) is a rabbit polyclonal antibody detecting WDR46 in ELISA, IHC, WB. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human WDR46 (Lys187-Glu523).

Cible

WDR46, C6orf11, BING4, WD repeat-containing protein BING4, WD repeat-containing protein 46

Purification

Purified by antigen affinity column.

Numéro d'accès

O15213

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

WD repeat-containing protein 46 (WDR46) is a ~68 kDa protein. Scaffold component of the nucleolar structure. Required for localization of DDX21 and NCL to the granular compartment of the nucleolus. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.

1. Hirai, Y. et al. (2013) Genes to cells : devoted to molecular & cellular mechanisms 18, 780-97. PMID: 23848194

2. Singh, S. et al. (2021) Science (New York, N.Y.) 373, eabj5338. PMID: 34516797

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-WDR46 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Hela cell lysate

Reférences

Fiche technique

Anti-Human WDR46 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human WDR46 Polyclonal Antibody (HT164014)

Aperçu

Images

Reférences

Fiche technique

SDS