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Anti-Human WIPI1 Polyclonal Antibody (HD292014)

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Vista general
Número de catálogoHD292014
Descripción
Anti-Human WIPI1 Polyclonal Antibody (HD292014) is a rabbit polyclonal antibody detecting WIPI1. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human WIPI1 (Leu17-Leu360).
Objetivo Atg18 protein homolog, WD repeat domain phosphoinositide-interacting protein 1, WD40 repeat protein interacting with phosphoinositides of 49 kDa, WIPI 49 kDa, WIPI-1, WIPI1, WIPI49
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q5MNZ9
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

WD repeat domain phosphoinositide-interacting protein 1 (WIPI1) is a ~48 kDa protein. Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. Plays an important role in starvation- and calcium-mediated autophagy, as well as in mitophagy. Functions downstream of the ULK1 and PI3-kinases that produce phosphatidylinositol 3-phosphate (PtdIns3P) on membranes of the endoplasmic reticulum once activated. Binds phosphatidylinositol 3-phosphate (PtdIns3P), and maybe other phosphoinositides including PtdIns3,5P2 and PtdIns5P, and is recruited to phagophore assembly sites at the endoplasmic reticulum membranes. There, it assists WIPI2 in the recruitment of ATG12-ATG5-ATG16L1, a complex that directly controls the elongation of the nascent autophagosomal membrane.

1. Proikas-Cezanne, T. et al. (2004) Oncogene 23, 9314-25. PMID: 15602573
2. Grotemeier, A. et al. (2010) Cellular signalling 22, 914-25. PMID: 20114074
3. Geeraert, C. et al. (2010) The Journal of biological chemistry 285, 24184-94. PMID: 20484055
4. Itakura, E. et al. (2010) Autophagy 6, 764-76. PMID: 20639694
5. Gaugel, A. et al. (2012) Journal of molecular signaling 7, 16. PMID: 23088497
6. Bakula, D. et al. (2017) Nature communications 8, 15637. PMID: 28561066
7. Maeda, S. et al. (2019) eLife 8. PMID: 31271352
8. Kojima, W. et al. (2021) Autophagy 17, 2011-2036. PMID: 33499712
Nota For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human WIPI1 Polyclonal Antibody

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