

| Numéro de catalogue | HB523014 | ||||||||
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| Description |
Anti-Human XAF1 Polyclonal Antibody (HB523014) is a rabbit polyclonal antibody detecting XIAP-associated factor 1; BIRC4-binding protein; XAF1; BIRC4BP; XIAPAF1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant human XAF1 (Met1-Asp175). | ||||||||
| Cible | XIAP-associated factor 1; BIRC4-binding protein; XAF1; BIRC4BP; XIAPAF1 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q6GPH4 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | XIAP-associated factor 1 (XAF1) is a ~34 kDa protein. Seems to function as a negative regulator of members of the IAP (inhibitor of apoptosis protein) family. Inhibits anti-caspase activity of BIRC4. Induces cleavage and inactivation of BIRC4 independent of caspase activation. Mediates TNF-induced apoptosis and is involved in apoptosis in trophoblast cells. May inhibit BIRC4 indirectly by activating the mitochondrial apoptosis pathway. | ||||||||
| Note | For research use only |
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