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| カタログ番号 | HP972014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human YEATS2 Polyclonal Antibody (HP972014) is a rabbit polyclonal antibody detecting YEATS2 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human YEATS2 (Asp196-Gly335). | ||||||||
| ターゲット | YEATS2, KIAA1197, YEATS domain-containing protein 2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9ULM3 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | YEATS domain-containing protein 2 (YEATS2) is a ~150 kDa protein. Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. 1. Wang, YL. et al. (2008) The Journal of biological chemistry 283, 33808-15. PMID: 18838386 2. Guelman, S. et al. (2009) Molecular and cellular biology 29, 1176-88. PMID: 19103755 3. Zhao, D. et al. (2016) Cell research 26, 629-32. PMID: 27103431 | ||||||||
| 注意事項 | For research use only. |
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