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| カタログ番号 | HT044014 | ||||||||
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| 説明 |
Anti-Human YJEFN3 Polyclonal Antibody (HT044014) is a rabbit polyclonal antibody detecting YJEFN3. Suitable for Human.
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human YJEFN3 (Met1-Leu299). | ||||||||
| ターゲット | AIBP2, ApoA-I-binding protein 2, YJEFN3, YjeF N-terminal domain-containing protein 3, YjeF_N3, hYjeF_N3 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | A6XGL0 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | YjeF N-terminal domain-containing protein 3 (YJEFN3) is a ~32 kDa protein. May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endothelium, a type of specialized endothelium manifesting hematopoietic potential. YJEFN3-mediated cholesterol efflux activates endothelial SREBF2, the master transcription factor for cholesterol biosynthesis, which in turn transactivates NOTCH and promotes hematopoietic stem and progenitor cell emergence. May play a role in spermiogenesis and oogenesis. 1. Rudolph, C. et al. (2007) Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 39, 322-35. PMID: 17533573 | ||||||||
| 注意事項 | For research use only |
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