

| Número de catálogo | HP671014 | ||||||||
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| Descripción |
Anti-Human ZBTB18 Polyclonal Antibody (HP671014) is a rabbit polyclonal antibody detecting ZBTB18 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human ZBTB18 (Met1-Thr128). | ||||||||
| Objetivo | Zinc finger and BTB domain-containing protein 18, RP58, TAZ1, ZNF238, Transcriptional repressor RP58, Translin-associated zinc finger protein 1, TAZ-1, Zinc finger protein C2H2-171, Zinc finger protein 238, ZBTB18, 58 kDa repressor protein | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q99592 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Zinc finger and BTB domain-containing protein 18 (ZBTB18) is a ~58 kDa protein. Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus. | ||||||||
| Nota | For research use only. |
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