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Anti-Human ZBTB48 Polyclonal Antibody (HY492014)

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Vista general
Número de catálogoHY492014
Descripción
Anti-Human ZBTB48 Polyclonal Antibody (HY492014) is a rabbit polyclonal antibody detecting ZBTB48 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human ZBTB48 (Val289-Leu628).
Objetivo Telomere zinc finger-associated protein, TZAP, Krueppel-related zinc finger protein 3, hKR3, Zinc finger and BTB domain-containing protein 48, Zinc finger protein 855, ZBTB48, HKR3, TZAP, ZNF855
Purificación Purified by antigen affinity column.
Número de acceso P10074
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Zinc finger and BTB domain-containing protein 48 (ZBTB48) is a ~77 kDa protein. Plays a critical role in transcriptional regulation and chromatin remodeling. Acts as a regulator of telomere length. Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres. Also acts as a transcription regulator that binds to promoter regions.

1. Li, JS. et al. (2017) Science (New York, N.Y.) 355, 638-641. PMID: 28082411
2. Jahn, A. et al. (2017) EMBO reports 18, 929-946. PMID: 28500257
3. Yoon, JH. et al. (2014) The Journal of biological chemistry 289, 4018-31. PMID: 24382891
4. Sugawara, M. et al. (1994) Molecular and cellular biology 14, 8438-50. PMID: 7969177
Nota For research use only.
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Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human ZBTB48 Polyclonal Antibody

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