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| カタログ番号 | HP019014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ZC3H4 (Glu417-Gly503). | ||||||||
| ターゲット | KIAA1064, C19orf7, ZC3H4, Zinc finger CCCH domain-containing protein 4 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9UPT8 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Zinc finger CCCH domain-containing protein 4 (ZC3H4) is a ~140 kDa protein. RNA-binding protein that suppresses transcription of long non-coding RNAs (lncRNAs). LncRNAs are defined as transcripts more than 200 nucleotides that are not translated into protein. Together with WDR82, part of a transcription termination checkpoint that promotes transcription termination of lncRNAs and their subsequent degradation by the exosome. The transcription termination checkpoint is activated by the inefficiently spliced first exon of lncRNAs. 1. Austenaa, LMI. et al. (2021) Nature structural & molecular biology 28, 337-346. PMID: 33767452 2. Estell, C. et al. (2021) eLife 10. PMID: 33913806 | ||||||||
| 注意事項 | For research use only. |
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