Anti-Human ZC3HAV1 Polyclonal Antibody (HP394014)

Name: Anti-Human ZC3HAV1 Polyclonal Antibody
Brand: abinScience
SKU: HP394014
Price: 168 USD
Availability: InStock

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SDS

Обзор

Каталожный номер

HP394014

Описание

Anti-Human ZC3HAV1 Polyclonal Antibody (HP394014) is a rabbit polyclonal antibody detecting ZC3HAV1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human ZC3HAV1 (Met1-Asn227).

Цель

Zinc finger CCCH-type antiviral protein 1, Zinc finger CCCH domain-containing protein 2, ZC3HAV1, ZC3HDC2, ZAP, Zinc finger antiviral protein, ARTD13, PARP13, ADP-ribosyltransferase diphtheria toxin-like 13, Inactive Poly [ADP-ribose] polymerase 13

Очистка

Purified by antigen affinity column.

Номер доступа

Q7Z2W4

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) is a ~101 kDa protein. Antiviral protein which inhibits the replication of viruses by recruiting the cellular RNA degradation machineries to degrade the viral mRNAs. Binds to a ZAP-responsive element (ZRE) present in the target viral mRNA, recruits cellular poly(A)-specific ribonuclease PARN to remove the poly(A) tail, and the 3'-5' exoribonuclease complex exosome to degrade the RNA body from the 3'-end. It also recruits the decapping complex DCP1-DCP2 through RNA helicase p72 (DDX17) to remove the cap structure of the viral mRNA to initiate its degradation from the 5'-end. Its target viruses belong to families which include retroviridae, including human immunodeficiency virus type 1, filoviridae: ebola virus (EBOV) and marburg virus (MARV), togaviridae: sindbis virus (SINV) and Ross river virus (RRV). Specifically targets the multiply spliced but not unspliced or singly spliced HIV-1 mRNAs for degradation.

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human ZC3HAV1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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