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| カタログ番号 | HA989023 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA, IF, IP | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | C19 | ||||
| ターゲット | RBSN, ZFYVE20, Rabenosyn-5, 110 kDa protein, FYVE finger-containing Rab5 effector protein rabenosyn-5, RAB effector RBSN, Zinc finger FYVE domain-containing protein 20 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q9H1K0 | ||||
| RRID | Anti-Human ZFYVE20 Antibody (C19) (abinScience Cat# HA989023, RRID:AB_3729222) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Rabenosyn-5 (RBSN) is a ~88 kDa protein. Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3). 1. Nielsen, E. et al. (2000) The Journal of cell biology 151, 601-12. PMID: 11062261 2. de Renzis, S. et al. (2002) Nature cell biology 4, 124-33. PMID: 11788822 3. Naslavsky, N. et al. (2004) Molecular biology of the cell 15, 2410-22. PMID: 15020713 4. Navaroli, DM. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, E471-80. PMID: 22308388 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human ZFYVE20 Antibody (C19)
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中国武漢市深敦寺路666号C棟、武漢、430206
