

| Número de catálogo | HP941014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human ZFYVE27 (Lys361-Lys411). | ||||||||
| Objetivo | Spastic paraplegia 33 protein, SPG33, ZFYVE27, Protrudin, Zinc finger FYVE domain-containing protein 27 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q5T4F4 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
||||||||
| Información de uso del producto |
| ||||||||
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Protrudin (ZFYVE27) is a ~45 kDa protein. Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections. 1. Shirane, M. et al. (2006) Science (New York, N.Y.) 314, 818-21. PMID: 17082457 2. Saita, S. et al. (2009) The Journal of biological chemistry 284, 13766-13777. PMID: 19289470 3. Hashimoto, Y. et al. (2014) The Journal of biological chemistry 289, 12946-61. PMID: 24668814 4. Chang, J. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 14954-9. PMID: 23969831 5. Matsuzaki, F. et al. (2011) Molecular biology of the cell 22, 4602-20. PMID: 21976701 | ||||||||
| Nota | For research use only. |
Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.
Correo: [email protected]
+86-027-65523339
Edificio C, No. 666, Calle Shendunsi, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский