Anti-Human ZNF143 Polyclonal Antibody (HW561014)

Name: Anti-Human ZNF143 Polyclonal Antibody
Brand: abinScience
SKU: HW561014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

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Número de catálogo

HW561014

Descripción

Anti-Human ZNF143 Polyclonal Antibody (HW561014) is a rabbit polyclonal antibody detecting ZNF143 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human ZNF143 (Gly263-Thr438).

Objetivo

STAF, SPH-binding factor, Selenocysteine tRNA gene transcription-activating factor, Zinc finger protein 143, ZNF143, SBF, hStaf

Purificación

Purified by antigen affinity column.

Número de acceso

P52747

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Zinc finger protein 143 (ZNF143) is a ~68 kDa protein. Transcription factor that activates expression of genes transcribed by both RNA polymerases II and III, and which is required to safeguard mitochondrial activity. Specifically recognizes and binds the Staf-binding site (SBS), a consensus DNA-binding motif present in thousands of promoters. Activates the gene for selenocysteine tRNA (tRNAsec). Activates expression of small nuclear RNA (snRNA) transcribed by RNA polymerases II and III. Also activates expression of mRNAs and acts as a key regulator of cell proliferation and differentiation by specifically activating expression of a subset of nuclear-encoded mitochondrial genes, thereby controlling mitochondrial function.

1. Kubota, H. et al. (2000) The Journal of biological chemistry 275, 28641-8. PMID: 10893243

2. Grossman, CE. et al. (2004) The Journal of biological chemistry 279, 12190-205. PMID: 14702349

3. Yuan, CC. et al. (2007) Molecular and cellular biology 27, 8729-38. PMID: 17938208

4. Vinckevicius, A. et al. (2015) Molecular and cellular biology 35, 4135-46. PMID: 26416877

5. Narducci, DN. et al. (2025) Molecular cell 85, 9-23.e9. PMID: 39708803

6. Myslinski, E. et al. (1998) The Journal of biological chemistry 273, 21998-2006. PMID: 9705341

7. Rincon, JC. et al. (1998) Nucleic acids research 26, 4846-52. PMID: 9776743

8. Myslinski, E. et al. (2006) The Journal of biological chemistry 281, 39953-62. PMID: 17092945

9. Anno, YN. et al. (2011) Nucleic acids research 39, 3116-27. PMID: 21177654

10. Ngondo-Mbongo, RP. et al. (2013) Nucleic acids research 41, 4000-14. PMID: 23408857

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human ZNF143 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human ZNF143 Polyclonal Antibody (HW561014)

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Referencias

Datasheet

SDS