Anti-Human ZNF143 Polyclonal Antibody (HW561014)

Name: Anti-Human ZNF143 Polyclonal Antibody
Brand: abinScience
SKU: HW561014
Price: 168 USD
Availability: InStock

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Каталожный номер

HW561014

Описание

Anti-Human ZNF143 Polyclonal Antibody (HW561014) is a rabbit polyclonal antibody detecting ZNF143 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human ZNF143 (Gly263-Thr438).

Цель

STAF, SPH-binding factor, Selenocysteine tRNA gene transcription-activating factor, Zinc finger protein 143, ZNF143, SBF, hStaf

Очистка

Purified by antigen affinity column.

Номер доступа

P52747

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Zinc finger protein 143 (ZNF143) is a ~68 kDa protein. Transcription factor that activates expression of genes transcribed by both RNA polymerases II and III, and which is required to safeguard mitochondrial activity. Specifically recognizes and binds the Staf-binding site (SBS), a consensus DNA-binding motif present in thousands of promoters. Activates the gene for selenocysteine tRNA (tRNAsec). Activates expression of small nuclear RNA (snRNA) transcribed by RNA polymerases II and III. Also activates expression of mRNAs and acts as a key regulator of cell proliferation and differentiation by specifically activating expression of a subset of nuclear-encoded mitochondrial genes, thereby controlling mitochondrial function.

1. Kubota, H. et al. (2000) The Journal of biological chemistry 275, 28641-8. PMID: 10893243

2. Grossman, CE. et al. (2004) The Journal of biological chemistry 279, 12190-205. PMID: 14702349

3. Yuan, CC. et al. (2007) Molecular and cellular biology 27, 8729-38. PMID: 17938208

4. Vinckevicius, A. et al. (2015) Molecular and cellular biology 35, 4135-46. PMID: 26416877

5. Narducci, DN. et al. (2025) Molecular cell 85, 9-23.e9. PMID: 39708803

6. Myslinski, E. et al. (1998) The Journal of biological chemistry 273, 21998-2006. PMID: 9705341

7. Rincon, JC. et al. (1998) Nucleic acids research 26, 4846-52. PMID: 9776743

8. Myslinski, E. et al. (2006) The Journal of biological chemistry 281, 39953-62. PMID: 17092945

9. Anno, YN. et al. (2011) Nucleic acids research 39, 3116-27. PMID: 21177654

10. Ngondo-Mbongo, RP. et al. (2013) Nucleic acids research 41, 4000-14. PMID: 23408857

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human ZNF143 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

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Anti-Human ZNF143 Polyclonal Antibody (HW561014)

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