

| Numéro de catalogue | HT432014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human ZNF263 Polyclonal Antibody (HT432014) is a rabbit polyclonal antibody detecting ZNF263 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ZNF263 (Lys375-Tyr546). | ||||||||
| Cible | Zinc finger protein 263, Zinc finger protein FPM315, Zinc finger protein with KRAB and SCAN domains 12, ZNF263, FPM315, ZKSCAN12 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O14978 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Zinc finger protein 263 (ZNF263) is a ~77 kDa protein. Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor. Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression. Acts as a transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions. 1. Yu, Z. et al. (2020) Oncogene 39, 3163-3178. PMID: 32051553 2. Weiss, RJ. et al. (2020) Proceedings of the National Academy of Sciences of the United States of America 117, 9311-9317. PMID: 32277030 | ||||||||
| Note | For research use only. |
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