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| カタログ番号 | HT432014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human ZNF263 Polyclonal Antibody (HT432014) is a rabbit polyclonal antibody detecting ZNF263 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ZNF263 (Lys375-Tyr546). | ||||||||
| ターゲット | Zinc finger protein 263, Zinc finger protein FPM315, Zinc finger protein with KRAB and SCAN domains 12, ZNF263, FPM315, ZKSCAN12 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O14978 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Zinc finger protein 263 (ZNF263) is a ~77 kDa protein. Transcription factor that binds to the consensus sequence 5'-TCCTCCC-3' and acts as a transcriptional repressor. Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression. Acts as a transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions. 1. Yu, Z. et al. (2020) Oncogene 39, 3163-3178. PMID: 32051553 2. Weiss, RJ. et al. (2020) Proceedings of the National Academy of Sciences of the United States of America 117, 9311-9317. PMID: 32277030 | ||||||||
| 注意事項 | For research use only. |
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